Which of the following is a criterion for C-I drugs?

C-I drugs, classified as Schedule I controlled substances, are characterized primarily by their high potential for abuse. This designation reflects the understanding that these substances have no accepted medical use in the United States and are deemed unsafe for use, even under medical supervision.

Because of the high potential for abuse associated with C-I drugs, such as heroin and LSD, they are subjected to the strictest regulations. The lack of accepted medical use also means that these drugs do not have any recognized therapeutic benefits in standard medical practice, which further emphasizes their high-risk status.

Conversely, drugs classified under different schedules may exhibit characteristics such as accepted medical uses, lower potential for abuse, or lead to limited physical dependence, which are not applicable to C-I substances. This distinction is crucial for understanding the regulatory landscape that governs controlled substances and their implications for medical practice and law.