Which act established the requirement for certain drugs to be accurately labeled with their contents and dose?

The Pure Food and Drug Act was pivotal in the history of pharmaceutical regulation as it introduced significant measures to ensure the safety and effectiveness of drugs. This act, enacted in 1906, established government oversight for the labeling and quality of food and medications. It specifically mandated that certain drugs must be accurately labeled with their contents and dosage information, addressing the rampant issue of misbranding and adulteration in the marketplace at that time.

By requiring truthful labeling, the Pure Food and Drug Act aimed to protect consumers from harmful substances and misleading claims, a critical step towards modern pharmacological safety standards. This focus on accurate labeling laid the groundwork for subsequent legislation that further developed drug regulation, including amendments that built upon the principles established by the Pure Food and Drug Act.

In contrast, the other acts mentioned, such as the Food Drug and Cosmetic Act and the Humphrey-Hurham Amendment, while significant in their own right, focused on more specific aspects of drug regulation and did not establish the foundational requirement for accurate labeling that the Pure Food and Drug Act created.