What must be noted on C-II controlled substance invoices?

When documenting transactions involving C-II controlled substances, it is critical to include sellers' and buyers' details, including addresses. This requirement is essential for maintaining the integrity of the controlled substance distribution system and ensuring compliance with legal regulations. Recording these details helps establish a clear chain of custody for the controlled substances, which is vital in preventing misuse and ensuring accountability.

Moreover, having this information allows for easier tracking and auditing by regulatory agencies, thereby reinforcing the overall security measures surrounding the handling of high-potential for abuse medications. The inclusion of both parties' details ensures that any discrepancies can be traced back to the responsible entities, facilitating law enforcement efforts when necessary.

In contrast, factors like the quantity of drugs alone, the methodology of drug administration, or a patient's insurance details do not provide the critical transaction information necessary for regulatory compliance and accountability within the pharmaceutical supply chain.