What is a key requirement for C-II prescriptions regarding refills?

C-II prescriptions are subject to strict regulations due to their high potential for abuse and dependence. One of the fundamental requirements is that they cannot be refilled at all. This regulation is established to ensure that controlled substances are monitored closely and dispensed only when a new prescription is presented by the patient. As a result, to obtain a C-II medication, the patient must see their healthcare provider for a new prescription each time they need a refill, thus minimizing the risk of misuse and ensuring that ongoing treatment is still appropriate for the patient's condition. This rule is crucial for maintaining patient safety and complying with federal and state laws governing controlled substances.